The Science Behind
Duori Patches

Twelve targeted wellness patches. Each one built on the same foundation: clinically studied ingredients, formulations engineered for transdermal delivery, and manufacturing standards that never compromise on quality.

Built for Delivery, Not Just for Labels

Most supplement companies optimize for ingredient lists. Duori optimizes for what actually reaches your bloodstream.

The supplement industry has a delivery problem. You can pack a capsule with high-dose ingredients, but if your body only absorbs 10–20% of what you swallow, the label is misleading. Duori was built to solve this.

Every Duori patch starts with the same question: can this ingredient be effectively delivered through the skin? We evaluate molecular weight, lipophilicity, stability, and potency before an ingredient makes it into a formulation. If it doesn't meet our transdermal viability criteria, it doesn't go in the patch — no matter how good it looks on a label.

The result is a lineup of 12 patches where every ingredient is selected not just for its clinical evidence, but for its ability to be absorbed transdermally. This is what separates Duori from supplements that simply repackage oral formulas into a patch format.

The Foundation of Every Duori Patch

From ingredient sourcing to the adhesive on your skin — every layer of a Duori patch is engineered with purpose.

Advanced Adhesive Matrix

Our medical-grade, pressure-sensitive adhesive is hypoallergenic and latex-free. It serves a dual purpose: keeping the patch secure through 8–12 hours of activity (including workouts and showers), while acting as the controlled-release delivery vehicle for active ingredients. The matrix regulates the rate at which ingredients permeate through the skin — eliminating spikes and crashes.

Optimized Formulations

We don't use generic oral-supplement-grade ingredients. Each Duori formula uses ingredient forms with molecular weights and lipophilicity profiles specifically suited for transdermal absorption. Ingredients are combined at ratios designed for synergistic effects — where the whole delivers more than the sum of its parts. This is formulation science, not label decoration.

Rigorous Quality Standards

Every Duori patch is manufactured in GMP-compliant facilities. Each batch is tested for ingredient purity, adhesion strength, release rate consistency, and overall integrity. Our formulas are dermatologist-tested, vegan, non-GMO, and cruelty-free. We publish our ingredient lists transparently because we have nothing to hide.

From Research to Patch — Our 4-Step Process

Every Duori formulation goes through a rigorous development process before it reaches your skin.

Research

Literature Review

We review published clinical research to identify ingredients with strong evidence for each wellness target — weight management, sleep, focus, skin health, or gut balance.

Screen

Transdermal Viability

Candidates are screened for molecular weight (<500 Da), lipophilicity (Log P 1–3), potency at low doses, and stability in a patch matrix. Only ingredients that pass all criteria advance.

Formulate

Synergistic Design

Qualified ingredients are combined into formulations where compounds complement each other — for example, pairing NMN with Resveratrol for cellular energy, or Berberine with Chromium for metabolic support.

Validate

Test & Manufacture

Finalized formulas undergo dermatologist testing, adhesion testing, and release rate validation. Manufacturing follows GMP standards with batch-level quality control.

12 Patches, 5 Wellness Categories

Each Duori patch targets a specific wellness goal with a unique formulation optimized for transdermal delivery.

Weight Loss & GLP-1

GLP-1 Weight Loss Patch

Supports natural GLP-1 pathways for appetite regulation, metabolic function, and healthy weight management through clinically studied plant compounds.

Berberine Chromium EGCG Garcinia Cambogia Gymnema Sylvestre
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Sleep & Recovery

Sleep Patch & Sleep+ Patch

Two tiers of sleep support — from gentle relaxation to deep recovery. Formulated with calming botanicals and sleep-promoting compounds for restorative rest.

Melatonin Ashwagandha L-Theanine Magnesium Valerian Root
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Focus & Mental Clarity

Neuro Patch & NAD+ Patch

Stimulant-free cognitive support. The Neuro Patch targets daily focus while the NAD+ Patch supports long-term brain health and cellular energy production.

Lion's Mane NMN CoQ10 Cordyceps Resveratrol
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Skin & Beauty

Collagen Patch

Transdermal delivery of collagen-supporting peptides and antioxidants for skin elasticity, hydration, and a healthy glow — from the inside out.

Collagen Peptides Vitamin C Hyaluronic Acid Biotin
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Gut & Metabolism

Unbloat Patch & Flora Patch

Digestive support through dual pathways — the Unbloat Patch targets bloating and discomfort, while the Flora Patch supports healthy gut microbiome balance.

Ginger Extract Peppermint Fennel Probiotics
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Mood & Vitality

Happy, Sunshine & Omega-3

Three patches targeting mood, energy, and foundational nutrition. From serotonin support to vitamin D and essential fatty acids — daily vitality, simplified.

5-HTP Vitamin D3 Omega-3 (DHA/EPA) B-Complex
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How We Test Every Batch

Trust is earned through transparency. Here's what every Duori patch goes through before it ships.

Dermatologist Testing

Every formula is tested by board-certified dermatologists for skin safety, irritation potential, and hypoallergenic compatibility. We test on diverse skin types to ensure broad safety.

Ingredient Purity Analysis

Raw ingredients are tested for identity, potency, and contaminants before entering production. We verify that what's on the label is exactly what's in the patch — nothing more, nothing less.

Adhesion Performance

Patches are tested for 8–12 hour wear under real-world conditions — movement, perspiration, and varying temperatures. The adhesive must hold securely without causing irritation on removal.

Release Rate Validation

Each formulation is tested for controlled, consistent ingredient release over the full wear period. We validate that delivery follows a steady-state profile — no front-loading, no premature depletion.

About Duori Patches

Everything you want to know about how we build, test, and deliver our patches.

Duori patches are formulated specifically for transdermal delivery — not repackaged oral ingredients. Every formula uses ingredient forms optimized for skin permeation, a medical-grade hypoallergenic adhesive matrix, and is manufactured in GMP-compliant facilities. Each batch undergoes dermatologist testing for safety and consistency.
Yes. Every Duori patch formula is dermatologist-tested for skin safety. Our patches are vegan, non-GMO, cruelty-free, and free from common irritants. Manufacturing follows Good Manufacturing Practice (GMP) standards, and each batch is tested for ingredient consistency, adhesion performance, and purity.
Ingredient selection follows a three-part framework: clinical evidence (published research supporting efficacy), transdermal viability (molecular weight under 500 Daltons, appropriate lipophilicity for skin permeation), and synergistic formulation (ingredients that complement each other for the target wellness goal). If an ingredient fails any of these criteria, it doesn't make the cut.
Duori uses a medical-grade, pressure-sensitive adhesive matrix that is hypoallergenic and latex-free. The adhesive serves a dual purpose: it keeps the patch securely in place for 8–12 hours during all activities, and it acts as the delivery vehicle, holding active ingredients in a controlled-release matrix for steady absorption throughout the day.
Duori offers 12 targeted wellness patches spanning five main categories: Weight Loss and GLP-1 support, Sleep and Recovery, Focus and Mental Clarity, Skin and Beauty, and Gut and Metabolism. Additional patches support mood, energy, and foundational nutrition. Each pack delivers a 30-day supply.
Duori patches are manufactured in facilities that follow Good Manufacturing Practice (GMP) standards. Every batch undergoes multi-point quality control: ingredient purity testing, adhesion strength testing, release rate validation, and overall product integrity checks before distribution.
Yes. Duori patches are designed to be stackable. Many customers wear two or three patches simultaneously on different areas of the body — for example, Neuro + NAD+ for cognitive support, or Sleep + Collagen for overnight recovery. Each patch delivers its ingredients independently, so stacking is both safe and effective.
Plant-powered means the active ingredients in Duori patches are derived from natural botanical and plant-based sources — such as Lion's Mane mushroom, Berberine, Ashwagandha, and Green Tea Extract (EGCG). These are combined with bioactive compounds like CoQ10, NMN, and 5-HTP that are selected for their clinical evidence and transdermal compatibility.

Science You Can
Wear Every Day

Twelve patches. Five wellness goals. One standard: every ingredient earns its place through clinical evidence and transdermal viability.

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Vegan & cruelty-free

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning any new supplement routine.