Prescription GLP-1 drugs cost $1,000+ a month, require injections, and come with waiting lists. Duori's botanical GLP-1 Support Patch delivers Berberine, Gymnema, and Bitter Melon transdermally — no prescription, no needles, no compromise.
Botanical supplement — not a pharmaceutical. Not affiliated with Novo Nordisk or Eli Lilly.
You have tried the pills, the shakes, the restrictive diets. Here is why they keep falling short.
Semaglutide and tirzepatide are effective — but with supply shortages, insurance battles, and out-of-pocket costs exceeding $12,000 a year, access remains a barrier for most people.
Most over-the-counter weight loss supplements are loaded with caffeine, ephedrine, or synthetic thermogenics that cause jitters, anxiety, and sleep disruption — the opposite of sustainable wellness.
Berberine — one of the most studied metabolic compounds — is notorious for poor oral bioavailability and GI side effects. Most of what you swallow never reaches your bloodstream.
The GLP-1 Support Patch bypasses your digestive system entirely — delivering botanical compounds directly through your skin into the bloodstream.
Peel, press, forget. Apply to clean, dry skin on your inner forearm or upper arm in the morning. Press firmly for 20 seconds.
Botanical compounds cross the skin barrier directly into your bloodstream — bypassing the gut entirely. No nausea, no GI irritation.
Berberine, Gymnema, and Bitter Melon work over 8 hours to support metabolic pathways associated with GLP-1 signalling, satiety, and healthy blood sugar.
Every ingredient targets a specific mechanism — AMPK activation, blood sugar regulation, appetite signalling, and mitochondrial energy support.
One of the most studied natural compounds for metabolic health. Berberine activates AMPK — often called the body's metabolic master switch — which research suggests may support healthy blood glucose levels, insulin sensitivity, and fat oxidation. Over 12 clinical studies have examined berberine's role in metabolic regulation.
Known in Ayurvedic medicine as the "sugar destroyer." Gymnema temporarily reduces sweet taste perception, helping blunt sugar cravings. Research suggests it may also support healthy insulin function and reduce sugar absorption.
Contains compounds structurally similar to insulin that may support healthy blood sugar and stimulate GLP-1 satiety signalling. Traditionally used in Ayurvedic and Chinese medicine for metabolic wellness.
Supports mitochondrial energy metabolism and acts as a powerful antioxidant. Studies suggest ALA may support metabolic efficiency and reduce oxidative stress associated with weight management.
Essential trace mineral that enhances insulin action and supports cellular glucose uptake. Research suggests chromium supplementation may support blood sugar stability between meals and reduce carbohydrate cravings.
Oral berberine is notorious for stomach issues. The patch format solves that — and delivers four additional benefits.
Ingredients absorbed transdermally skip the liver's first-pass breakdown — more of each compound reaches systemic circulation where it supports your metabolism directly.
No spike-and-crash cycle. The patch releases compounds steadily throughout the day — unlike a capsule that peaks and drops within 1-2 hours.
Oral berberine is well-known for causing nausea, cramping, and diarrhoea. Transdermal delivery bypasses the digestive system entirely — no GI side effects.
No timing around meals, no remembering to take a pill three times a day. Apply once in the morning and your metabolic support works passively for 8 hours.
Botanical satiety and blood sugar support — delivered transdermally for 8 hours, stimulant-free.
Botanical satiety and blood sugar support via metabolic pathways associated with GLP-1 signalling — stimulant-free, 8-hour transdermal release.
$24 / 30 patches
That's just $0.80 per day
Consistency is everything. Here is what customers typically report over their first 8 weeks.
Blood sugar support kicks in early. Most users notice fewer afternoon crashes and less desire to snack between meals within the first two weeks.
Satiety signalling from Gymnema and Bitter Melon compounds over time. Meals feel more satisfying, portion control becomes easier without willpower effort.
Berberine's AMPK activation and fat oxidation support begin showing measurable effects. Combined with a balanced diet, users typically see body composition changes by this stage.
Consistent daily use compounds metabolic benefits. This is where most customers see their most significant results — and why the 3-Pack is the most popular order.
The GLP-1 Support Patch supports your metabolism — it works best as part of an active, intentional lifestyle, not as a standalone fix. Pair it with balanced nutrition and regular movement for the clearest results.
Start your 30-day routine →* Individual results vary. Timeline based on customer self-reports and published ingredient research, not clinical trials of this specific product. The GLP-1 Support Patch is a botanical supplement, not a weight loss drug.
An honest, informational comparison to help you make the right choice for your wellness journey.
4.8 stars from 450+ verified reviews. Real customers, real results — no paid testimonials.
"I was sceptical about a GLP-1 'patch' but after reading the ingredients I gave it a shot. The cravings control is real — I just feel less hungry, especially in the afternoons when I used to raid the kitchen. Combined with walking 30 minutes a day, I'm finally seeing the scale move."
✓ Verified"I tried oral berberine supplements for months but the stomach cramps were unbearable. This patch gives me the same appetite control without any GI issues at all. I've been using it for 6 weeks and my afternoon energy is noticeably better. Worth every penny."
✓ Verified"I'm not going to pretend the patch alone made me lose weight — but it absolutely took the edge off my sweet cravings, my energy is more stable, and I'm eating smaller portions without trying. Down 9 lbs in 8 weeks with balanced eating and daily walks."
✓ VerifiedNo. The Duori GLP-1 Support Patch is a botanical wellness supplement — not a pharmaceutical drug. It contains plant-based compounds like Berberine, Gymnema Sylvestre, and Bitter Melon that research suggests may support metabolic pathways associated with GLP-1 signalling through AMPK activation. It is not a GLP-1 receptor agonist and is not equivalent to prescription medications such as semaglutide (Ozempic/Wegovy) or tirzepatide (Mounjaro/Zepbound). Always consult your healthcare provider.
Five key botanical compounds: Berberine HCl (AMPK activation and blood sugar support), Gymnema Sylvestre (sugar craving reduction and insulin support), Bitter Melon Extract (blood sugar regulation and satiety signalling), Alpha-Lipoic Acid (mitochondrial energy and antioxidant support), and Chromium Picolinate (insulin sensitivity and glucose metabolism). All ingredients are plant-derived. The patch is vegan and cruelty-free.
Apply to clean, dry skin on your inner forearm, upper arm, or shoulder blade after showering in the morning. Press firmly for 20 seconds. The patch releases botanical compounds steadily over 8 hours. Remove after 8 hours and rotate to a fresh skin site the next day to prevent sensitivity.
Berberine and other botanical compounds in the patch may interact with certain medications, particularly diabetes medications, blood thinners, and blood pressure medications. Always consult your healthcare provider before starting any new supplement, especially if you are currently taking prescription medications.
Yes. The GLP-1 Support Patch contains zero caffeine, ephedrine, or synthetic thermogenics. It works through metabolic regulation via plant-based compounds, not stimulation. It is safe for daily use and will not cause jitters, crashes, or sleep disruption.
Most users notice reduced cravings and more stable energy within the first 1–2 weeks. Improved appetite regulation typically develops over weeks 3–4. Visible metabolic changes with consistent use alongside a balanced diet are most commonly reported between weeks 6–8. Individual results vary. The patch works best as part of an active, intentional lifestyle.
Duori offers a 60-day money-back guarantee on all products. If you are not satisfied with the GLP-1 Support Patch, contact hello@duoripatches.com within 60 days for a full refund.
Both the GLP-1 Support Patch and prescription GLP-1 medications affect blood sugar pathways. Using them together without medical supervision is not recommended. If your doctor has prescribed a GLP-1 medication such as Ozempic, Wegovy, Mounjaro, or Zepbound, continue to follow their guidance and consult your prescribing physician before adding any supplement.
Yes. The GLP-1 Support Patch is formulated for daily use. Rotate application sites each day to avoid skin sensitivity. All patches are dermatologist-tested, vegan, cruelty-free, and free from synthetic stimulants. If you are pregnant, nursing, or managing a medical condition, consult your healthcare provider before use.
Oral berberine is known for causing gastrointestinal side effects including nausea, cramping, and diarrhoea — a major reason many people stop taking it. Transdermal delivery bypasses the digestive system entirely, absorbing compounds directly through the skin into the bloodstream. This avoids GI irritation and provides a sustained 8-hour release rather than the spike-and-crash pattern of a capsule.
That's $0.63/day for 90 days of botanical GLP-1 support.
Shop the 3-Pack — $48 →One patch. One morning. Eight hours of botanical GLP-1 support — without the prescription, without the injection, without the side effects.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. The Duori GLP-1 Support Patch is a botanical wellness supplement and is not a substitute for prescription GLP-1 receptor agonist medications such as semaglutide (Ozempic/Wegovy) or tirzepatide (Mounjaro/Zepbound). Always consult a healthcare professional before starting any new supplement programme, especially if you are pregnant, nursing, taking prescription medications, or managing a medical condition.
